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Leuprolide Acetate 1 mg

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Lupride Injection belongs to the class of ‘anticancer or anti-neoplastic agents’, primarily used to treat prostate cancer in men, breast cancer and endometriosis in women and precocious puberty (early puberty) in children. Prostate cancer is the prostate gland’s cancer (a small gland under the bladder secretes fluid that nourishes and protects sperm) found only in men. Breast cancer is a type of cancer that develops in breast cells stimulated by a female sex hormone called oestrogen. Endometriosis is a disorder in which tissue lining the uterus grows outside the uterine cavity. Precocious puberty occurs when a child’s body changes into that of an adult or experiences puberty too soon.

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Leuprolide Acetate 1 mg is a gonadotropin-releasing hormone (GnRH) agonist used in the management of hormone-sensitive conditions, including:

  • Prostate cancer (palliative treatment)

  • Endometriosis

  • Uterine fibroids

  • Central precocious puberty (CPP)

  • Assisted reproductive technologies (ART) protocols

It works by initially stimulating, then significantly suppressing, the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to decreased production of testosterone in men and estrogen in women.

The 1 mg formulation is typically administered as a daily subcutaneous injection and may be part of a short-term or transitioning regimen before longer-acting depot versions.


Key Benefits:

  • Reduces testosterone or estrogen levels for hormone-sensitive conditions

  • Used in palliative care for advanced prostate cancer

  • Controls painful symptoms of endometriosis and fibroids

  • Manages early onset puberty in children (CPP)

  • Often used in IVF cycles to control hormonal timing

  • Quick onset with flexible dosing schedules


Product Details:

  • Generic Name: Leuprolide Acetate

  • Strength: 1 mg per vial or prefilled syringe

  • Form: Injectable solution (subcutaneous)

  • Route: Subcutaneous injection (usually daily)

  • Packaging: Single-dose vial or prefilled syringe


Important Safety Information:

  • May cause an initial hormone surge (“flare-up”) in the first week of treatment

  • Common side effects: hot flashes, headache, mood swings, decreased libido

  • In men: monitor for urinary obstruction or bone pain during initial treatment

  • In women: long-term use may lead to bone mineral density loss

  • Not recommended during pregnancy or breastfeeding

  • Should only be administered under medical supervision


1. What is Leuprolide Acetate 1 mg used for?

It is used to treat hormone-dependent conditions like prostate cancerendometriosisuterine fibroids, and central precocious puberty.


2. How is it administered?

Leuprolide 1 mg is given once daily via subcutaneous injection, usually in the abdomen or thigh.


3. Is it safe for long-term use?

It may be used long-term under medical supervision, but bone density, hormone levels, and cardiovascular healthshould be monitored.


4. Does it cause side effects?

Yes. Common side effects include hot flashes, sweating, headache, decreased libido, and mood changes. Men may experience a temporary flare in symptoms during the first week.


5. Can women use Leuprolide 1 mg?

Yes, it’s used in women to manage endometriosisfibroids, and as part of fertility treatment protocols. However, long-term use can affect bone health.


6. How quickly does it work?

Leuprolide begins to act within days, but hormone suppression is typically achieved within 2 to 4 weeks.

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