Tolvaptan tablets 15mg

Tolvaptan 15 mg Tablets are a prescription medication used to treat hyponatremia (low blood sodium levels), especially in patients with heart failure, cirrhosis, or SIADH (Syndrome of Inappropriate Antidiuretic Hormone Secretion). Manufactured by various pharmaceutical companies, Tolvaptan works as a selective vasopressin V2-receptor antagonist, helping your body restore normal sodium levels through water excretion without losing electrolytes.

Key Features:

• Active Ingredient: Tolvaptan 15 mg
• Drug Class: Vasopressin Antagonist (Vaptan class)
• Primary Use: Treatment of hyponatremia in euvolemic and hypervolemic conditions
• Form: Oral tablet
• Route of Administration: By mouth, once daily
• Storage: Store at room temperature away from light and moisture

How It Works

Tolvaptan works by blocking the vasopressin V2 receptors in the kidneys. This action prevents water reabsorption, causing the body to excrete more water through urine while retaining essential electrolytes. The result is an increase in serum sodium levels, making it especially effective for conditions like SIADH, congestive heart failure, or liver cirrhosis-related hyponatremia.

Recommended Dosage

• Initial dose: 15 mg once daily
• May be increased to 30 mg and then to 60 mg at 24-hour intervals if needed
• Not recommended for use beyond 30 consecutive days
• Monitor blood sodium and hydration status regularly during use

Possible Side Effects

Common side effects:

• Increased thirst
• Dry mouth
• Frequent urination
• Fatigue
• Nausea

Serious but rare effects:

• Liver toxicity (watch for yellowing of skin or eyes)
• Dehydration symptoms (dizziness, weakness)
• Rapid sodium correction (risk of osmotic demyelination)

Precautions & Warnings

• Use only under the supervision of a healthcare provider
• Not suitable for patients with significant liver impairment
• Not recommended in patients unable to sense or respond to thirst
• Pregnant or breastfeeding women should consult a doctor before use
• Avoid grapefruit juice – it may interfere with the metabolism of Tolvaptan