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Tolvaptan tablets 30mg
Tolvaptan (Samsca) is used to treat hyponatremia (low levels of sodium in the blood) in people who have heart failure (condition in which the heart cannot pump enough blood to all parts of the body), syndrome of inappropriate antidiuretic hormone (SIADH; condition in which the body produces too much of a certain natural substance that causes the body to retain water) or other conditions.
Tolvaptan Tablets 30mg is a prescription medication belonging to the class of vasopressin receptor antagonists. It works by blocking the action of vasopressin (antidiuretic hormone) on the kidneys, thereby promoting water excretion without significant loss of electrolytes.
It is primarily used in the management of:
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Clinically significant hyponatremia (low serum sodium levels) associated with heart failure, cirrhosis, or SIADH.
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Autosomal Dominant Polycystic Kidney Disease (ADPKD), to slow down the progression of cyst development and kidney function decline (in some treatment guidelines and specific approvals).
Key Benefits:
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Corrects low sodium levels effectively.
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Helps reduce symptoms such as confusion, nausea, seizures, or fatigue due to hyponatremia.
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Improves quality of life in patients with chronic conditions like heart failure or kidney disease.
Dosage & Administration:
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Usual starting dose is 15mg once daily, which may be titrated up to 30mg or 60mg based on response and tolerance.
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Tolvaptan therapy should be initiated and monitored under the supervision of a healthcare professional.
Safety Information:
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Regular monitoring of liver function and serum sodium is required.
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Not recommended in patients with hypovolemic hyponatremia, severe liver impairment, or those unable to respond to thirst.
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Common side effects may include thirst, dry mouth, polyuria (frequent urination), constipation, or increased liver enzymes.
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