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Low Dose Naltrexone 3 mg

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Low Dose Naltrexone (LDN) 3 mg is a specially compounded form of Naltrexone, used in significantly lower doses than the standard 50 mg. While full-dose Naltrexone is FDA-approved for opioid and alcohol dependence, LDN is increasingly used off-label as a potential immune system modulator and anti-inflammatory aid.

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Taken at doses between 1.5 mg to 4.5 mg, LDN 3 mg is believed to help balance immune function and reduce chronic inflammation. It has gained popularity for managing symptoms in conditions such as fibromyalgiamultiple sclerosis (MS)chronic fatigue syndrome (CFS)autoimmune diseasesCrohn’s diseaseHashimoto’s thyroiditis, and more.

LDN works by temporarily blocking opioid receptors at night, which may increase the body’s production of endorphins and improve immune regulation.


Key Benefits:

  • Modulates immune system function in autoimmune and inflammatory conditions

  • May reduce symptoms of chronic pain, fatigue, and inflammation

  • Potentially helpful in fibromyalgia, MS, Crohn’s disease, and thyroid disorders

  • Non-addictive and non-sedating

  • Compounded formulation for optimal low-dose therapy

  • Usually well-tolerated with minimal side effects


Product Details:

  • Active Ingredient: Naltrexone Hydrochloride

  • Strength: 3 mg

  • Form: Oral capsules or tablets (depending on compounder)

  • Usage: Typically taken once daily at bedtime

  • Storage: Store in a cool, dry place away from sunlight


Important Safety Information:

  • Use only under the supervision of a qualified healthcare provider

  • Do not use if you are currently taking opioid medications — may cause withdrawal

  • May cause vivid dreams, sleep disturbances, or mild headache in some users

  • Not FDA-approved for autoimmune or inflammatory uses (off-label use)

  • Consult your doctor before combining with thyroid or immune-modulating medications


1. What is Low Dose Naltrexone 3 mg used for?

It is used off-label to help manage autoimmune and inflammatory conditions such as fibromyalgia, MS, lupus, and thyroid disorders.


2. How does LDN work?

LDN briefly blocks opioid receptors, which may stimulate endorphin release and help regulate the immune system.


3. How should I take LDN 3 mg?

It is usually taken once daily at bedtime, as nighttime dosing may enhance endorphin response.


4. Are there any side effects?

LDN is generally well tolerated. Some users may experience vivid dreams, headaches, or sleep disturbances, especially when starting treatment.


5. Can I take LDN while on opioids?

No. LDN should not be taken with opioid medications or painkillers, as it can block their effects and trigger withdrawal.


6. Is LDN 3 mg FDA-approved for autoimmune diseases?

No, LDN is used off-label for these conditions. It is not approved by the FDA for immune or inflammatory disorders but is widely prescribed in integrative and functional medicine.

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