Naltrexone

Low Dose Naltrexone (LDN) — typically 1.5 mg to 4.5 mg — is also used off-label for autoimmune diseases, chronic pain, fibromyalgia, and inflammation-related conditions by modulating the immune system.

Available Strengths

• Naltrexone 50 mg tablets (standard prescription strength)
• Low Dose Naltrexone (1.5 mg, 3 mg, 4.5 mg)

Key Benefits

• Reduces cravings and risk of relapse in alcohol or opioid addiction
• Non-habit-forming and non-sedating
• LDN may reduce inflammation and modulate immune function
• Safe for long-term use under supervision

How It Works

Naltrexone blocks opioid receptors in the brain, preventing opioid or alcohol-induced euphoria. In low doses, it temporarily blocks endorphin receptors, causing a rebound effect that may help regulate immune and neurological function.

Common Uses

• Opioid use disorder
• Alcohol use disorder
• Low Dose: Multiple sclerosis, fibromyalgia, Crohn’s disease, Hashimoto’s thyroiditis, long COVID (off-label)

FAQs

1. What is Naltrexone used for?

Naltrexone is approved for alcohol and opioid dependence. Low Dose Naltrexone (LDN) is used off-label for autoimmune and chronic inflammatory diseases.

2. Can I take Naltrexone if I am on opioids?

No. Naltrexone will block the effects and may trigger withdrawal symptoms if opioids are still in your system.

3. Are there side effects?

Possible side effects include nausea, headache, dizziness, fatigue, and insomnia. These are usually mild and temporary.

4. How is LDN different from standard Naltrexone?

LDN uses much lower doses (1.5–4.5 mg) and is used off-label for different therapeutic effects, especially for immune and neurological conditions.